Screening for metabolic disorders in children with autism is not cost-effective, according to a study published 7 July in PLoS One. The researchers argue instead for careful individual clinical analysis.

Some of the same genetic risk factors may underlie both autism and attention deficit hyperactivity disorder, according to a study published 10 August in Science Translational Medicine.

Children with autism who carry a certain variant of a protein involved in inhibitory signaling have more severe symptoms than those with another variant of the same gene, according to a study published 24 July in the Journal of Autism and Developmental Disorders.

New studies of restricted and repetitive behaviors link autism to other disorders and may lead to more effective treatments.

MeCP2, the protein missing in people with Rett syndrome, enhances learning and memory by binding to key genes and either activating or inhibiting their expression, according to a study published 17 July in Nature Neuroscience. Adding a phosphate to the protein in response to neuronal activity releases MeCP2 from these genes, the study found.

The brains of teenagers with autism and their unaffected siblings respond similarly to both happy and neutral faces, whereas those of controls seem to prefer happy ones, according to a study published 12 July in Translational Psychiatry.

Children who have more than one older sibling with autism have a one in three chance of developing the disorder themselves, according to a study published today in Pediatrics. The risk is higher for boys: Even if they have only one older sibling with autism, they are almost three times more likely than girls with the same family history to develop the disorder.

Toddlers with autism are less likely to use gestures to communicate than are typically developing children and those with developmental delay or specific language impairment.

Autism studies tend to focus on one part of the spectrum, often excluding those who also have other conditions such as anxiety, obsessive-compulsive disorder or intellectual disability. The result, some experts say, is piecemeal findings that don’t fit together to generate a whole picture.

Genetic variants in two autism-associated genes have been linked to repetitive behavior and hyperactivity, two common symptoms of the disorder, according to two studies published in the past few months.