Common and rare autism-linked variants share functional effects
Within the 16p region of the genome, the two types of variants similarly decrease neuronal gene expression — an effect that may reflect their spatial relationship.
Within the 16p region of the genome, the two types of variants similarly decrease neuronal gene expression — an effect that may reflect their spatial relationship.
The model enables the study of autism-linked genes at the earliest stages of neural development.
The signal, called CD47, is disrupted in autistic people who have a larger-than-average head.
The function of microglia and astrocytes in the brain may mediate the intersection of sex-differential biology and autism biology.
Using imaging methods to sort mouse models of autism may help identify subtypes of autistic people with similar underlying biology.
Brain cell clusters serve as drug screens and reveal connectivity differences for autism-linked conditions, two new models show.
This week we’re highlighting the Twitter chatter from the Society for Neuroscience’s annual meeting, held in San Diego, California, last week.
Pagani used mouse models to connect autism etiologies to brain connectivity alterations and then found similar alterations in people with idiopathic forms of the condition.
New studies bolster the idea that zebrafish models can say something meaningful about social behavior in autism.
Brain scans of the hippocampus reveal autistic people who are at increased risk of cognitive problems as they get older.