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Spectrum: Autism Research News

News Archive

December 2022
X chromosome against a dark background.

Common and rare autism-linked variants share functional effects

by  /  1 December 2022

Within the 16p region of the genome, the two types of variants similarly decrease neuronal gene expression — an effect that may reflect their spatial relationship.

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November 2022
Image displaying impeded interneuron development.

‘Assembloids’ lay bare autism-linked genes that hamper neuron development

by  /  30 November 2022

The model enables the study of autism-linked genes at the earliest stages of neural development.

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Geometric black-and-white brain model over a grid.

Excess of ‘don’t eat me’ cell signals may drive brain enlargement in autism

by  /  22 November 2022

The signal, called CD47, is disrupted in autistic people who have a larger-than-average head.

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Light micrograph of microglia cells stained with Rio Hortega’s silver carbonate method.

Autism’s sex bias tied to glial, immune cell gene expression

by  /  22 November 2022

The function of microglia and astrocytes in the brain may mediate the intersection of sex-differential biology and autism biology.

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Grid of nine mri scans of mouse brains.

Shared brain structure, connectivity hint at autism subgroups

by  /  21 November 2022

Using imaging methods to sort mouse models of autism may help identify subtypes of autistic people with similar underlying biology.

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Image of organoids modeling CDKL5 deficiency disorder.

Organoids identify potential therapies, circuit flaws for autism-linked syndromes

by  /  21 November 2022

Brain cell clusters serve as drug screens and reveal connectivity differences for autism-linked conditions, two new models show.

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Speech bubble formed by a network of communication

Community Newsletter: Highlights from Neuroscience 2022

by  /  20 November 2022

This week we’re highlighting the Twitter chatter from the Society for Neuroscience’s annual meeting, held in San Diego, California, last week.

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Marco Pagani stands in front of his research poster.

Subtyping autism using fMRI: A quick take at SfN with Marco Pagani

by  /  18 November 2022

Pagani used mouse models to connect autism etiologies to brain connectivity alterations and then found similar alterations in people with idiopathic forms of the condition.

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Still image from video of zebrafish swimming in small enclosures.

Zebrafish social behavior swims into mainstream

by  /  17 November 2022

New studies bolster the idea that zebrafish models can say something meaningful about social behavior in autism.

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An older woman with gray hair sits on a couch and speaks with a clinician.

Brain’s memory center flags autistic adults at risk for cognitive decline

by  /  17 November 2022

Brain scans of the hippocampus reveal autistic people who are at increased risk of cognitive problems as they get older.

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