UBE3A, a key gene associated with both autism-linked conditions, can explain most — but not all — of the syndromes’ atypical neuronal properties.
Spectrum: Autism Research News
Pagani used mouse models to connect autism etiologies to brain connectivity alterations and then found similar alterations in people with idiopathic forms of the condition.
Brain scans of the hippocampus reveal autistic people who are at increased risk of cognitive problems as they get older.
The circuit linking the prefrontal cortex and part of the thalamus is impaired in mice raised in social isolation and in mice with mutations in the FMR1 or TSC2 genes.
Zebrafish with mutations in 10 different autism-linked genes show a range of unique and shared phenotypes.
A range of presentations at Neuroscience 2022 tie atypical social behavior to trouble discriminating between odors in the animals.
Work in fruit flies has helped Paul decode a neurodevelopmental syndrome in children caused by rare de novo variants in the gene PPFIA3.
The temporary easing of traits that a minority of autistic children are reported to show during or after a fever may stem from a rise in body temperature.
Scott describes his work on sound processing differences in the brains of zebrafish that model fragile X syndrome.