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Spectrum: Autism Research News

News Archive

November 2021
UBE3A expression in mouse brain slices, shown in green.

One-shot gene therapy for Angelman syndrome shows promise in mice

by  /  29 November 2021

A potential new gene therapy delivered via a single injection mimics ratios of proteins normally found in cells.

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A gloved-hand holds up a vial against a background of colorful lights that represent a sequenced genome.

Genetic effects stack up in some people with autism

by  /  23 November 2021

Rare variants that alter the expression of genes in the brain contribute to autism in people who also have a rare autism-linked mutation, according to a new study.

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Pink, blue and purple illustration shows a cell with mitochondria.

Mitochondria: An energy explanation for autism

by  /  22 November 2021

People with autism have more mutations than others do in both mitochondrial DNA and nuclear DNA that affects mitochondrial function.

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Many mouths making conversation, with speech bubbles in red and blue.

Community Newsletter: Which came first, the diet or the gut microbiota?

by  /  21 November 2021

In this week’s Community Newsletter, we look at discussions about the relationship between autism and the gut microbiome, plus a new single-cell chromatin remodeling atlas.

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Clinician sitting with young boy looking at drawings together.

Age at autism diagnosis, first intervention drops to under 3 years

by  /  19 November 2021

Autism diagnoses in the United States now precede developmental services and interventions, according to a new study.

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By the Numbers: Black neuroscience speakers, mildly effective CBT, autism’s diagnostic odyssey

by ,  /  19 November 2021

This edition of By the Numbers logs the continued underrepresentation of Black speakers at neuroscience meetings, mildly-effective cognitive behavioral therapy and early autism diagnoses.

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Synaptic overgrowth, hyperconnectivity may define autism subtype

by  /  18 November 2021

Model mice of the subtype also show hyperactivity in a signaling pathway called mTOR, bolstering the idea that distinct forms of autism have different biological roots and may require different treatment approaches.

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Cognitive behavioral therapy may be only mildly effective for anxious, autistic children

by  /  16 November 2021

Many autistic children rate the therapy as less effective at treating their anxiety than their parents and clinicians do.

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Illustration shows a cartoon-like simple figure made out of a switchboard, with colorful cables converging on an area deep in the brain.

Brain’s sensory switchboard has complex connections to autism

by  /  15 November 2021

An atypical thalamus may underlie not only sensory issues in autism but also difficulties with social skills, attention and memory.

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Including immune cells in brain organoids improves model’s accuracy

by  /  15 November 2021

Cortical organoids that contain non-neuronal brain cells called microglia may reflect human neurodevelopment more faithfully than those that don’t.

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