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Spectrum: Autism Research News

News Archive

February 2023
Speech bubble formed by a network of communication

Community Newsletter: Autism assessment; cognitive aging; metabolic diseases

by  /  5 February 2023

Discussion among autism researchers on Twitter this week swirled around how well pediatricians assess the condition, how it affects cognitive aging and how it alters cardiometabolic disease risk.

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A white mouse, brown mouse and black mouse stand inside a wooden circle against a blue background.

CHD8 mutation in 33 mouse strains yields range of traits

by  /  3 February 2023

The findings put genetic background forward to help explain autism’s heterogeneity.

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Headshot of Johnny Matson, former editor-in-chief of Research in Developmental Disabilities and Research in Autism Spectrum Disorders.

Prolific autism researcher has two dozen papers retracted

by  /  2 February 2023

Elsevier’s retractions focus on peer review and conflicts of interest.

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Research image comparing neurons that lack the ZFP462 gene to wildtype neurons.

Autism-tied gene ZNF462 keeps developing neurons on track

by  /  1 February 2023

The gene, linked to a little-known condition called Weiss-Kruszka syndrome, prevents embryonic stem cells from deviating from their neuronal destiny.

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January 2023
Research image showing the impact of a gene mutation on a synapse.

Tweaks to autism-linked pathway tilt circuits’ signaling balance

by  /  31 January 2023

Altered expression of TSC2 and the mTOR pathway reshape the formation of certain synapses between inhibitory and excitatory neurons in mice.

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Many mouths making conversation, with speech bubbles in red and blue.

Community Newsletter: Better measurement; Rett rescue; interactomes; social touch

by  /  29 January 2023

Conversation took off this week around precision in neuroscience measurements, a new strategy to rescue Rett neurons, autism insights from protein interactomes, and mechanisms of touch perception.

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Two adult prairie voles snuggle.

‘Mind-blowing’ study upends conventional wisdom on oxytocin

by  /  27 January 2023

CRISPR-edited prairie voles that lack receptors for the so-called “social hormone” still bond with their mate and pups, raising questions about the molecule’s role.

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A multiracial group of schoolchildren sit at their desks in class.

Racial, economic disparities skew New Jersey data on autism, intellectual disability

by  /  26 January 2023

Serious differences in autism identification persist, according to an analysis of autistic children in New Jersey over 16 years.

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A hand reaches from above to add a pill to a stack that is resting against the x-axis of a graph.

Going on Trial: Arbaclofen reboot; cell implants; psilocybin microdoses

by  /  25 January 2023

Going on Trial rounds up new developments in autism-related drug trials. This month we’re revisiting decade-old data from a trial of arbaclofen for fragile X syndrome and looking into a new implant-based approach to quelling seizures, among other treatment strategies.

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Research image showing neuronal activity in mice exposed to high-frequency sounds.

Missing mechanism helps solve fragile X protein mystery

by  /  24 January 2023

Cells from people with fragile X syndrome overproduce — but don’t accumulate — proteins. New work suggests that excessive protein breakdown may account for this discrepancy, and explain some of the syndrome’s traits.

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