NEWS

Society for Neuroscience 2017

November 2017
lab mouse in scientists hand with blue gloves
SFN 2017

Selective enzyme block reveals new treatment for fragile X

by  /  14 November 2017

A drug that selectively blocks one form of an enzyme called GSK-3 prevents seizures and improves cognitive deficits in a mouse model of fragile X syndrome.

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mouse running up wheel
SFN 2017

Experimental Huntington’s drug improves gait in Rett mice

by  /  14 November 2017

A candidate drug in clinical trials for Huntington’s disease reverses gait problems in a mouse model of Rett syndrome.

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Microglia (white), the brain’s resident immune cells, have been implicated in autism.
SFN 2017

Maternal asthma alters immune cells in fetal brain

by  /  14 November 2017

Mouse pups exposed to an immune response in the womb show autism-like behaviors and altered gene expression in brain cells called microglia.

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magnetic stimulation of human brain
SFN 2017

Magnetic stimulation bares imbalance of activity in fragile X brains

by  /  14 November 2017

Researchers have used transcranial magnetic stimulation to show that people with fragile X syndrome have weak ‘inhibitory’ signals, those that dampen neuronal activity in the brain.

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Organoids derived from fetal bone recapitulate brain development over the first 16 weeks of gestation.
SFN 2017

‘Mini-brains’ mirror fetal brain development

by  /  14 November 2017

Spheres of brain cells derived from a fetal skull have gene expression patterns similar to those in brain tissue from the same fetus.

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family of marmoset monkeys
SFN 2017

AI interprets marmosets’ trills, chirps and peeps

by  /  14 November 2017

New artificial intelligence software can decode conversations between small monkeys called marmosets.

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spongebob squarepants with an excited expression
SFN 2017

Grouping people with autism masks variations in visual learning

by  /  14 November 2017

Some young children with autism excel on tests in which they must learn to connect visual cues.

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six scans of brains showing various active regions highlighted
SFN 2017

Missing brain wave may explain language problems in nonverbal autism

by  /  14 November 2017

Nonverbal children with autism don't show the typical wave of brain activity involved in linking objects with their names.

3 Comments
ett syndrome drugs are unlikely to affect all neurons in the brain in the same way.
SFN 2017

Rett syndrome mutation’s effects vary by cell type

by  /  14 November 2017

Mutations in the Rett syndrome gene MECP2 have different effects on subtypes of neurons.

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monkey portrait
SFN 2017

Scientists move closer to gene therapy for Rett syndrome

by  /  14 November 2017

A virus that delivers a working copy of the Rett syndrome gene to the brain improves features of the condition in mice, and appears to be safe in monkeys.

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