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Society for Neuroscience Global Connectome 2021

January 2021
neurons in mice
SFN GC 2021

Sensory perception, cell signals disrupted in people and mice missing autism gene

by  /  13 January 2021

People and mice with only one working copy of the autism gene SYNGAP1 may have trouble processing sights and sounds.

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Mouse brain scan video still in black and white.
SFN GC 2021

New mouse brain atlas traces connections in fine detail

by  /  13 January 2021

A new wiring diagram of the mouse brain could help autism researchers better study how brain connections vary in mice with different genetic backgrounds.

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Face stimuli displaying neutral emotions and EEG electrode recording sites.
SFN GC 2021

Brain response to facial features may lag in autistic people

by  /  13 January 2021

Looking at eyes, noses and mouths may prompt slower recognition in the brains of autistic people than in those of non-autistic people.

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Baby getting an MRI scan
SFN GC 2021

Imaging study casts doubt on cerebellum’s role in autism during infancy

by  /  13 January 2021

Connections between the cerebellum and brain networks do not seem to contribute substantially to the emergence of autism traits.

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Four white mice on a rotarod, blue background.
SFN GC 2021

Motor skills, brain volume affected in mouse model of DDX3X syndrome

by  /  13 January 2021

Mice missing one copy of the autism-linked gene DDX3X have smaller brains and worse motor skills than mice with both copies of the gene, according to a new unpublished study.

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Two mice in a rotarod machine
SFN GC 2021

Mouse study sounds note of caution for Rett syndrome therapies

by  /  13 January 2021

Treatments for Rett syndrome that aim to boost levels of the protein MECP2 may not help everyone with the condition.

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SFN GC 2021

Zebrafish lacking oxytocin receptors skip school

by  /  13 January 2021

Model fish seem to spend more time swimming solo than wildtype zebrafish do, and neurochemicals in their brains respond differently to social interactions.

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Neurons in cerebella of mice with fewer branches and spines.
SFN GC 2021

Cerebellum alterations crop up in mice missing autism gene

by  /  12 January 2021

Deleting the autism-linked gene CNTNAP2 from mice leads to distinct cellular and electrical changes in the cerebellum, according to two unpublished studies presented virtually today at the 2021 Society for Neuroscience Global Connectome.

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Senior man lying down in scanning machine.
SFN GC 2021

Studies hint at effects of aging on autistic brains

by  /  12 January 2021

People with autism or autism traits may be especially vulnerable to brain aging and cognitive decline, two studies suggest.

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dopamine neurons in mice show up green in an area of the brain associated with social reward.
SFN GC 2021

Dopamine neurons may dampen social behavior in mouse model of autism

by  /  12 January 2021

Mice missing a copy of the autism-linked gene PTEN show a reduced preference for social interaction, possibly due to atypically large, overconnected dopamine neurons. Easing the overconnection may alleviate this trait.

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