The past few years have seen an unprecedented number of clinical trials for experimental drugs to treat autism-related disorders, most notably for fragile X syndrome. But as the trials progress, scientists are calling for better methods to measure the drugs’ effectiveness.

Clinical trials for fragile X drugs should include a behavioral therapy component, says a parent of a child with the disorder.

Identifying genetic and other factors that protect children at risk of autism from developing the disorder could provide new avenues for treatment.