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International Society for Autism Research 2022

INSAR 2022
Woman sits on a hospital bed and looks out of a window.

Psychiatric conditions hospitalize almost one in three autistic women by age 25

by  /  31 October 2022
The findings, based on Swedish national registry data, suggest a critical need to expand mental health services for autistic people.
INSAR 2022
Lab mice (Mus musculus), tribe Balbc, three 13 day old babies with eyes still closed, laying side by side

Sleepy mice with autism-linked mutation struggle to fall asleep

by  /  12 September 2022
Mice with a mutated copy of SHANK3 fail to establish normal sleep patterns during development.
INSAR 2022
A woman in a white lab coat uses a micropipette

Modified CRISPR tool boosts UBE3A levels in mice

by  /  20 May 2022
A deactivated form of the gene editor restores UBE3A expression in mice and human neurons without cutting the genome. It may hold promise for future Angelman gene therapies.
May 2022
INSAR 2022

Structural brain changes foretell language skills in autistic infants

by ,  /  19 May 2022

Increased white-matter maturation tracks with stronger language abilities later in childhood, but the relationship with cortical thickness is less clear.

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INSAR 2022

Researchers publish new dataset on minimally verbal autistic people

by  /  18 May 2022

Researchers at the Massachusetts Institute of Technology published the first repository of vocalizations from minimally verbal autistic people. Those with few or no spoken words still produce a range of phonemes, or units of sound, that may serve as developmental markers or intervention targets.

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Child in dark room with thermometer showing 100.8.
INSAR 2022

Fever doesn’t ease challenging traits in most autistic children

by  /  17 May 2022

The findings contradict a previous study, whose design may have been biased to find an effect.

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Young woman sitting alone at window in the shadows.
INSAR 2022

Autistic LGBTQ+ people report frequent mental health problems

by  /  16 May 2022

The co-occurring conditions may stem from the heightened stress people in minority communities experience.

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Three views of zebrafish.
INSAR 2022

Novel gene linked to brain size in autistic people

by  /  16 May 2022

The gene, YTHDF2, may be one of several that contribute to an autism subtype marked by an unusually big brain.

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INSAR 2022

Clinicians lack confidence in diagnostic interviews with Black mothers

by  /  13 May 2022

Implicit biases might be to blame, and the discrepancy persists across clinics, regardless of maternal education, family income and a child’s IQ score.

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INSAR 2022

Information loss may weaken autism genetic scores

by  /  13 May 2022

Even the best data practices and technology drop key variants in attempts to predict autism likelihood.

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Speech bubble formed by a network of communication
INSAR 2022

INSAR Community Newsletter: Tweets & murmurs from Day Three

by  /  13 May 2022

We are covering the talks in Austin, Texas, this week, plus what the research community is talking about online, in the Lone Star Ballroom and around town.

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INSAR 2022

Organoids hint at origins of enlarged brains in autistic people

by  /  13 May 2022

The size of the cerebral cortex seems to depend on when neural progenitor cells multiply or differentiate into glial cells and neurons.

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Neuron with dendrites, showing white on solid black.
INSAR 2022

DDX3X loss affects male, female mouse neurons differently

by  /  12 May 2022

The sex-specific effects may help elucidate why the small number of boys with DDX3X syndrome are born to unaffected mothers.

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