Spectrum: Autism Research News

The papers were flagged by a method that has now been called into question.

Blocking the enzyme, called TOP2A, in embryos makes the animals less inclined to seek companionship later in life.

A new method that merges tissue expansion, light-sheet microscopy and automated image segmentation can reconstruct neural circuits in about a week.

The open-source software makes it possible to overlay disparate datasets and potentially accelerate hypothesis generation.

The findings, based on Swedish national registry data, suggest a critical need to expand mental health services for autistic people.

This month’s newsletter also highlights deflated autism prevalence estimates from Shanghai, China.

Machine-learning tools are widely available and can help speed up studies in animal models of autism. Here’s how to get started with the ‘minimal viable product’ and a few pro tips.

Here is a roundup of news and research for the week of 16 May.

This edition plots school suspensions and the unemployment gap for autistic people, and charts outcomes for those who attend regular health checks.

A deactivated form of the gene editor restores UBE3A expression in mice and human neurons without cutting the genome. It may hold promise for future Angelman gene therapies.