Mice missing key clock gene show autism-like traits
A new study is the first to link social, repetitive and motor behaviors to mutations in BMAL1, which regulates the body’s circadian rhythms.
A new study is the first to link social, repetitive and motor behaviors to mutations in BMAL1, which regulates the body’s circadian rhythms.
Among the millions displaced by the war in Ukraine are children and adults with autism. Many autism professionals are doing what they can to help.
The temporary organ may hold clues about the origins of autism and brain development, Anna Penn says — if only researchers would study it.
In this edition, a strategy to help autistic children adapt their skills to new situations shows no benefit, but an early-life autism biomarker does.
Overexpressing genes involved in the pathway, which regulates protein quality, changes repetitive behaviors in the animals.
The gene, dubbed NHIP, is in a chromosomal region that shows unusually low levels of DNA methylation in placentas from women who gave birth to autistic children.
The neurons, which have low levels of the gene ASH1L, sprout more branches after the treatment.
In this edition of Null and Noteworthy, a large clinical trial goes sideways, while memory and emotions hold up.
The drug suppresses an overactive signaling pathway implicated in tuberous sclerosis complex.
The brain region, which is involved in fear and emotion processing, develops differently in autistic children with anxiety than in those without anxiety or in non-autistic children; its development also depends on the type of anxiety a child experiences.