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Spectrum: Autism Research News

Author

Angie Voyles Askham

Senior reporter

Angie Voyles Askham is Senior Reporter for Spectrum, where she covers neural circuits and gene therapy, among other topics. She proposed and writes Spectrum Launch, a monthly newsletter for early-career researchers. Before joining Spectrum in 2020, she worked in radio journalism and academic publishing. Voyles Askham has a Ph.D. in neuroscience from NYU and a bachelor’s degree in neuroscience from Vanderbilt University. You can email her at [email protected] or find her on Twitter @avaskham.

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November 2022
Light micrograph of microglia cells stained with Rio Hortega’s silver carbonate method.

Autism’s sex bias tied to glial, immune cell gene expression

by  /  22 November 2022

The function of microglia and astrocytes in the brain may mediate the intersection of sex-differential biology and autism biology.

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Grid of nine mri scans of mouse brains.

Shared brain structure, connectivity hint at autism subgroups

by  /  21 November 2022

Using imaging methods to sort mouse models of autism may help identify subtypes of autistic people with similar underlying biology.

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Illustration of multipolar neurons.

Consistent, convergent pathways link two forms of autism

by  /  15 November 2022

People with dup15q syndrome and those with idiopathic autism have similar patterns of altered gene expression in early brain development and later in life.

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Three-dimensional structure of cells in the cerebellum.

Flexible genomic architecture undergoes major redesigns during cerebellum development

by  /  13 November 2022

A new atlas reveals how the structural shake-ups within a cell’s genome differ by cell type and brain region over time.

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A hand holds a compass against a blue background.

Spectrum Launch: Child care at SfN; interview tips; Neuropixels course

by  /  3 November 2022

This month’s issue is packed with tips for early-career researchers heading to the first in-person meeting of the Society for Neuroscience in three years.

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October 2022
Jeremy Levin, chief executive officer of Ovid Therapeutics, stands against a bench in a lab.

What next for Angelman?

by  /  20 October 2022

A meeting in Texas reckons with the future of treatment, following two setbacks in 2020.

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Mouse brain slices showing the effects of SHANK2 and SHANK3 deletions.

Double SHANK knockout highlights brain circuit’s social role

by  /  19 October 2022

Mice missing the autism-linked SHANK2 and SHANK3 genes in their retrosplenial cortex have trouble distinguishing between novel and familiar mice.

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Photograph of a mouse nesting in a pile of hay.

Scoring mouse behaviors: Q&A with Michael Sidorov

by  /  17 October 2022

A new analysis package enables researchers to distill multiple measures of Angelman syndrome mice into a single ‘severity score.’

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Week of OctoberOct
10th
2022

Spotted around the web: Autism services for Indigenous people; seizure meds; brain waves

Here is a roundup of news and research for the week of 10 October.

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An illustration of a scientist sitting at a desk with abstract shapes representing ideas floating above her.

Designing autism-friendly trials: Q&A with Caroline Averius and Zachary Williams

by  /  7 October 2022

The pair’s new guidebook offers practical steps to make clinical trials easier and more meaningful for autistic participants.

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