‘Splice-switching’ strategy boosts SYNGAP1 expression
The approach improves the function of SYNGAP1-deficient neurons in vitro, but whether it will work in people remains unclear.
The approach improves the function of SYNGAP1-deficient neurons in vitro, but whether it will work in people remains unclear.
UBE3A, a key gene associated with both autism-linked conditions, can explain most — but not all — of the syndromes’ atypical neuronal properties.
Here is a roundup of news and research for the week of 13 March.
Methodological choices and study-site artifacts confounded an attempt to replicate findings in support of an autism brain-imaging biomarker, according to new unpublished work.
The new tool may pose challenges for the scientific community, but used wisely, it can help researchers save time and resources.
Here is a roundup of news and research for the week of 27 February.
Mice and rats, for example, gravitate toward their mother’s bedding over bedding that is clean or smells of a different dam.
After a year of intense growth, funding for biotech is in decline. The result is layoffs and program cuts — and maybe some innovation.
Here is a roundup of news and research for the week of 13 February.
The treatment eases the animals’ sleep troubles, suggesting it has clinically meaningful effects beyond what was thought to be a critical window in early life.