Jacob Vorstman wants to help people who have rare mutations tied to autism, schizophrenia and other neurodevelopmental conditions set expectations about outcomes.
Cells with excess UBE3A, an autism-linked protein, have atypical firing properties that can be corrected by limiting the protein’s levels, according to new research.
Two unpublished studies detail improved techniques for delivering gene therapies to the brain.
Sensory problems in people with fragile X syndrome may stem from hyperactive neurons, a mouse model study suggests.
Mutations in two genes linked to autism and intellectual disability boost the immune response and cause synapse dysfunction.
A novel microscopy technique offers the most detailed look to date at the proteins present at neuronal junctions.
Even when they share identical genetic backgrounds, mice from separate litters show different patterns of development, according to a new study.
Mutations in POGZ, a gene strongly linked to autism, lead to a signaling imbalance in multiple brain regions in mice, according to two new studies.
Autistic people are at an increased risk for intentional self-harm and death by suicide, but co-occurring psychiatric conditions may drive those behaviors.
Ami Klin wants researchers, clinicians and policymakers to think of autism as something inborn that only predisposes a child to certain traits. Early intervention can change the course of development.
